Trend Micro Systems
Without sounding too pompous...may I suggest Trend' PC-cillin, or as it is now called Trend Internet Security, from Trend Micro Systems.
Like the previous writer noted...I too have used a certain prog...Trend...since W95 came on the market, save for one tedious episode with Norton... I agree with Wombat, on this point only, that Norton products are resource magnets and tough as nails to get off your system without a lot of grunt time put in...although they do have the NRT to offer up, for download.
If you do not want the whole program, at least download and install their sysclean.com program, which runs in any mode...and it's free!!! I don't think that there is any other software "out there" that would work in the same manner, at least I have not tripped over it yet.