I have downloaded a few registry cleaners and nothing has worked I have about 8 file folders that are blank and wont me delete. A lot of them are from limewire which I have deleted but cant seem to delete these leftovers a few examples of the files are active x and some read as zedo[1].txt or tribalfusion[1].txt. What can I do to get rid of these things? Also, is there a special download to completely remove limewire? I noticed Kazaa by the way I have windows vista

You can try this,
SysChat - Downloads (Freeware Utilities) - Unlocker

Or MoveOnBoot
Download MoveOnBoot 1.95 - Allows you to copy, moves or delete files on the next system boot - Softpedia

Remember to back up before making changes, in case you delete something important.