hi ertm new here found this thread from google i have this problem too (using vista basic 64bit) i have a program set to run on startup that keeps asking for permision (i want it to run it allows me to use a joy pad in place of a mouse.) so i tryde ticking the "special permisions box and it wont let me i am the only user and have the only account (as admin) and it is set to "Full control" any idea why i still cant tick that box? (should i try putting all the program files in the system folder or something?)