I use the following:
 
Norton - AntiVirus and a Spyware Blocker
Spyware Doctor  - Spyware Remover
Acronis Privacy Expert Suite  
Microsoft AntiSpyware - Spyware Detector  
Spyware Blaster - Spyware Deleter (blaster)
Spybot - Search & Destroy  
I would recomend you 
ALL getting the ones in 
bold. 
You can find most of them on 
www.majorgeeks.com and they are FREE (ones in bold).  
I have so many because I go to A LOT of sites on the net.  I would say a few hundred + each day searching for stuff.